Animal DNA Testing

DDC Veterinary 1-800-625-0874


PKD DNA Testing for Cats

Polycystic Kidney Disease (PKD) is an inherited autosomal dominant disorder among Persian, Himalayan, and exotic cats. Characterized by the formation of cysts on the kidneys, PKD could lead to eventual renal failure and possible death.

PKD is dominant; therefore, heterozygotes (those possessing one copy of the mutation) will likely be clinically affected. When bred to genotypically normal cats, heterozygotes will still likely produce clinically affected offspring 50% of the time.

Anyone can collect feline DNA samples at home using a buccal (cheek) swab, and testing can be performed on cats of any age.

We will provide a detailed DNA report showing the cat’s genotype for PKD. The possible genotypes include: NN (2 copies of the normal allele) NP Heterozygote (1 normal copy and 1 copy of the PKD mutation), or PP (2 copies of the PKD mutation).

Below is a schematic showing how PKD is passed on to future generations. If you have additional questions about testing please feel free to call us at 1-800-625-0874 or email us at contact@vetdnacenter.com.

Polycystic Kidney Disease Inheritance

The following table shows the expected distribution of progeny genotypes based on a mating where both parents have known genotypes.

Legend:

N = Normal Allele
P = PKD Mutation

NN = 2 normal copies of the gene
NP = 1 normal copy, 1 copy of the PKD mutation
PP = 2 copies of the PKD mutation

 


Test Fee: $48 per Sample

Sample Type: Buccal Swab

Turnaround Time: 10 Business Days



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